What happens when there is an increase in capillary permeability?

When capillary permeability increases, the walls of the capillaries become more porous, allowing larger molecules and fluids to pass through them more easily. This leads to an outflow of fluids from the capillaries into the surrounding interstitial space, resulting in an accumulation of fluid in the interstitial areas. This process is often seen in conditions such as inflammation, where chemicals released in response to injury or infection increase the permeability of capillaries. The net effect of increased permeability is the movement of fluid into the interstitial space, causing an increase in interstitial fluid volume, which can lead to edema or swelling in the tissues.