What is the half-life of low molecular weight heparin?

The half-life of low molecular weight heparin (LMWH) is typically in the range of 12 to 24 hours. This relatively extended half-life is a key characteristic that differentiates LMWH from unfractionated heparin, which has a shorter half-life and often requires more frequent dosing. The longer half-life of LMWH allows for simpler dosing regimens, often enabling once or twice daily subcutaneous administration for the prevention and treatment of thromboembolic disorders. This pharmacokinetic profile contributes to its therapeutic convenience and effectiveness, making it a preferred choice in various clinical scenarios involving anticoagulation.