What structure does the GSV pass anterior to?

The great saphenous vein (GSV) is a major superficial vein in the leg that typically ascends along the medial side of the lower limb. When considering its course, one significant landmark it passes anterior to is the medial malleolar protuberance. This anatomical structure is the bony prominence located on the inner side of the ankle, where the tibia ends and forms the medial aspect of the ankle joint.

As the GSV travels proximally from the foot, it crosses anterior to this protuberance before continuing its ascent towards the thigh and eventually draining into the femoral vein in the groin. Understanding this relationship is key for both clinical practice and a comprehensive knowledge of venous anatomy in phlebology. The medial malleolar region is critical for many surgical and diagnostic procedures involving the veins of the lower extremities, thus reinforcing the importance of recognizing this anatomical position.