Which factor can lead to an increased risk of cerebral venous thrombosis in women?

The use of oral contraceptives is associated with an increased risk of cerebral venous thrombosis in women primarily due to the hormonal changes they induce. Estrogen, present in many oral contraceptives, can lead to a hypercoagulable state, which means the body is more prone to clot formation. This is particularly relevant because the cerebral venous system has unique blood flow characteristics, and an increase in clotting factors can significantly elevate the risk of venous thrombosis in brain veins.

Many studies have documented this risk, especially among women with additional risk factors, such as obesity, smoking, or a history of thromboembolic events. Understanding the hormonal impact of oral contraceptives is vital for assessing and managing the overall risk of thrombotic events in this population.